Cantargia reports high response rates with CAN04 combination therapy in NSCLC and presents next development steps
Cantargia AB today announced updated interim results from the ongoing clinical trial investigating the interleukin-1 receptor accessory protein (IL1RAP) blocking antibody CAN04 in combination with chemotherapy in non-small cell lung cancer (NSCLC). Tumor burden decreased in all 9 evaluable patients and in 6 of these patients, the decrease is large enough to be defined as a response. One patient treated for more than one year has an ongoing complete response and the other five have partial responses. The side effects are those expected from chemotherapy or CAN04. Neutropenia is more frequent