Brain astrocytes show metabolic alterations in Parkinson’s disease
A new study using induced pluripotent stem cell (iPSC) technology links astrocyte dysfunction to Parkinson’s disease (PD) pathology. The study carried out at the University of Eastern Finland and published in Scientific Reports highlights the role of brain astrocyte cells in PD pathology and the potential of iPSC-derived cells in disease modelling and drug discovery.
PD affects more than 6 million people worldwide, making PD the second most common neurodegenerative disease. PD's exact cause is still unknown, but several molecular mechanisms have been identified in PD pathology. These