Novel findings explain indirect regulation of glucose homeostasis
The hormone secreting part of the pancreas, the islets of Langerhans, has a unique cyto-architecture that allows functional interrelationships between the different cell types. Somatostatin is secreted by the delta cell and is an effective inhibitor of the insulin secreting beta cell and the glucagon secreting alpha cell. According to a novel study from Sweden’s Karolinska Instiutet, published in the journal Nature Communications, the delta cell can thereby indirectly affect glucose homeostasis in health and disease.Our results provide important insight into the activity of the delta cell