First clinical study successfully completed with X842, an innovative promising treatment for severe erosive GERD
The Basel, Switzerland-based biotech company Cinclus Pharma AG today announced that it has successfully completed the first clinical Phase 1 study of its lead compound X842, for the treatment of severe erosive Gastroesophageal reflux disease (Erosive GERD Grade C and D).The study showed that X842 was safe and well tolerated. The strongly validated biomarker for healing of erosive GERD (eGERD), intragastric acidity, was possible to maintain above pH 4 for 24 hours after a single dose. Such acid control indicates that 100% healing rate of eGERD is achievable. The trial was an open label,