COVID-19 infection alters gene transcription of olfactory mucosal cells in Alzheimer's disease
A new study identifies alterations in the transcriptomic signatures in human olfactory mucosal cells of individuals with Alzheimer's disease following SARS-CoV-2 infection, potentially contributing to exacerbated COVID-19 outcomes. The study was conducted at the University of Eastern Finland in collaboration with the University of Helsinki and published in Journal of Neuroinflammation. The study was prompted by concerns about the impact of COVID-19 on individuals with pre-existing conditions such as Alzheimer’s disease (AD). Olfactory dysfunction, characterized by an impaired sense of