New publication shows Cline’s gradient surfaces achieving faster and more efficient stem cell differentiation
In a new article published in the Journal of Biotechnology, Cline Scientific showed that gradient surfaces functionalized with Activin-A leads to improved, controllable and more efficient differentiation of stem cells compared to classical methods. Activin-A is an important biomolecule for the differentiation of stem cells into many different types of cells and organs. The team transformed induced pluripotent stem cells (iPSCs) into definitive endoderm (DE) which is the first step in generating many different cell linages and stem cell based applications. Cline's method not only allowed