Update on US review of roxadustat
11 August 2021 14:35 BST Update on US regulatory review of roxadustatin anaemia of chronic kidney disease The US Food and Drug Administration (FDA) has issued a complete response letter (CRL) regarding the New Drug Application (NDA) for roxadustat for the treatment of anaemia of chronic kidney disease (CKD), in both non-dialysis dependent (NDD) and dialysis-dependent (DD) adult patients. The CRL requested an additional clinical trial on the safety of roxadustat in both the NDD and DD patient populations. AstraZeneca is working with its partner FibroGen, Inc. (FibroGen) and the