UNION therapeutics A/S announces publication of results from the IASOS Phase 2b study of orismilast in psoriasis in Journal of the American Academy of Dermatology
· In the Phase 2b study, orismilast significantly reduced Psoriasis Area and Severity Index (PASI) compared with placebo from baseline to week 16 · 39.5% to 49.0% of patients treated with orismilast achieved PASI75 and 22.0% to 28.3% of patients achieved PASI90 · The clinical data supports the benefits of orismilast, a next-generation, high potency PDE4 B/D selective inhibitor · Orismilast is currently tested in an ongoing Phase 2b study in atopic dermatitis, and with recently reported positive topline Phase 2 results in hidradenitis suppurativa (HS) Hellerup, Denmark,