English version of PR published 20201012 at 07.33AM SynAct Pharma completes part 1 of clinical phase II study with AP1189 in Rheumatoid Arthritis
SynAct Pharma AB ("SynAct") today announced that dosing of the leading candidate drug AP1189 was successfully completed in the second cohort (100 mg dose level) in part 1 of the company’s Phase IIa study in patients with Rheumatoid Arthritis (RA) with high disease activity.A data review on blinded non-validated data from 15 patients in the cohort of 100 mg dosing suggests that the compound is safe and well tolerated and shows that two thirds of the patients (10/15 patients) had a reduction in disease activity from severe to moderate or low disease activity during the 4 weeks treatment