Cantargia publishes preclinical data on strong anti-tumor efficacy of nadunolimab in combination with chemotherapy
Cantargia (Cantargia AB; Nasdaq Stockholm: CANTA) today reported publication of preclinical results demonstrating that Cantargia’s lead candidate, the IL1RAP-binding antibody nadunolimab (CAN04), shows synergistic anti-tumor efficacy with chemotherapy through a mechanism likely to be highly relevant in the clinical situation. The effect is dependent on the unique capability of nadunolimab to simultaneously block both the alpha and beta forms of interleukin-1 (IL-1). These findings support the promising clinical interim data observed with nadunolimab in pancreatic cancer (PDAC) and non-small