Cantargia reports positive safety data from CIRIFOUR clinical study on nadunolimab and pembrolizumab combination
Cantargia AB today reported an interim update on the first part of the phase Ib clinical study CIRIFOUR. Fifteen cancer patients no longer responding to checkpoint inhibitor therapy received nadunolimab as an add-on to Keytruda® (pembrolizumab) with the primary objective to evaluate safety. The results show a very favorable safety profile, with only one treatment-related grade 3 toxicity identified. As one third of patients are still on therapy, efficacy is planned to be reported in Q2 2022. The next stage of CIRIFOUR will investigate this combination with chemotherapy in non-small cell lung