Unexpected effect of MS drug
Researchers at Karolinska Institutet in Sweden have studied the mechanism of action of a drug used to treat multiple sclerosis. The results, which are published in the journal Nature Communications, show that the drug affects cells in the innate immune system and that there is an unexpected link between therapeutic effect and an increase in the production of reactive oxygen species.Multiple sclerosis (MS) is an autoimmune disease that affects the central nervous system. The tablet Tecfidera (dimethyl fumarate, DMF) was approved a few years ago, but the exact mechanism of action of the drug