Traffic-related ultrafine particles hinder mitochondrial functions in olfactory mucosa
Ultrafine particles, UFPs, the smallest contributors to air pollution, hinder the function of mitochondria in human olfactory mucosa cells, a new study shows. Led by the University of Eastern Finland, the study showed that traffic-related UFPs impair mitochondrial functions in primary human olfactory mucosa cells by hampering oxidative phosphorylation and redox balance. Furthermore, the responses of olfactory mucosa cells of individuals with Alzheimer’s disease differed from those of cognitively healthy controls. The findings were published in Redox Biology. Air pollution forms a major