Cantargia presents new data at SITC 2022 supporting nadunolimab’s promising antitumor clinical efficacy
Data shows nadunolimab dual mechanism potently reduces levels of tumor-promoting molecules Cantargia (Cantargia AB; Nasdaq Stockholm: CANTA) today reported new data providing further insights to the mechanisms underlying the antitumor activity of the IL1RAP-binding antibody nadunolimab (CAN04). In a model of the pancreatic cancer (PDAC) microenvironment, nadunolimab potently reduced levels of various tumor-promoting molecules, in sharp contrast to an anti-IL-1β antibody which showed no such effects. PDAC and non-small cell lung cancer (NSCLC) patients treated with nadunolimab and