EMA approves the potential to dose every 14 days or longer in updated dosing regimen for Alprolix®
Swedish Orphan Biovitrum AB (publ) (Sobi™) has received approval from the European Medicines Agency (EMA) to update the dosing information for Alprolix® (eftrenonacog alfa). Alprolix is indicated for treatment and prophylaxis of bleeding in patients with haemophilia B (congenital factor IX deficiency), and it can be used for all age groups. The dosing information in the product information now includes that patients on long-term prophylaxis to protect against bleeding and who are well controlled on a 100 IU/kg once every 10 days regimen, might be treated on an