Holding(s) in Company
TR-1: Standard formfor notification ofmajor holdings NOTIFICATION OFMAJOR HOLDINGS (tobe sent to therelevantissuer and to theFCA in MicrosoftWord format ifpossible) 1a. Identity of the ASTRAZENECA PLCissuer or theunderlying issuer ofexisting shares towhich voting rightsare attached:1b. Please indicateif the issuer is anon-UKissuer (please markwith an "X" ifappropriate)Non-UK issuer2. Reason for thenotification (pleasemark the appropriatebox or boxes with an"X")An acquisition or