Tissue fluid flow can reveal onset of osteoarthritis
Reflecting the overall structural alterations in the tissue, changes in the flow of interstitial fluid in articular cartilage could be an indicator revealing the onset of osteoarthritis, according to a new study from the University of Eastern Finland. The PhD study of Janne Mäkelä, MSc, focused on structural and functional changes in articular cartilage at different stages of osteoarthritis. By using finite element modelling, the study combined structural data with functional data measured from articular cartilage samples. This enabled a detailed analysis of how individual structural