Cantargia presents new preclinical data showing unique improvement of heart function in myocarditis using antibody CAN10
Cantargia AB today presented new results on the antibody CAN10 at the annual meeting of the American Association of Immunologists (AAI), Virtual IMMUNOLOGY 2021. These data demonstrate that the interleukin-1 receptor accessory protein (IL1RAP)-binding antibody CAN10 reduces inflammation and/or fibrosis in several disease models including myocarditis. CAN10, which blocks signaling of IL-1, IL-33 and IL-36, counteracted deterioration of the cardiac function more potently than blockade of IL-1 signaling only.Cantargia develops antibody-based immunotherapies targeting IL1RAP. Cantargia’s most