Positive results from human PK study assessing Orexo’s new intranasal naloxone formulations for opioid overdose reversal
Uppsala, Sweden – January 7, 2019. Orexo AB (publ), the fully integrated specialty pharmaceutical company addressing opioid addiction and pain, today announces positive results from the human pharmacokinetic (PK) study OX124-001 in 20 healthy volunteers, assessing Orexo’s novel naloxone nasal spray formulations intended for opioid overdose reversal. The study was a cross-over, comparative, bioavailability study comparing four development formulations of OX124 to Narcan® Nasal Spray 4mg, the current market-leading naloxone rescue medication in the US. All formulations of OX124 were well