Researchers unraveled new mechanisms behind articular cartilage healing after injury
Understanding how the knee joint environment affects cartilage cells is crucial for joint health. Knowledge of cell-driven cartilage degeneration mechanisms can support the development of effective pharmaceutical interventions for osteoarthritis.The burden of musculoskeletal diseases, such as osteoarthritis, is increasingly affecting patients’ quality of life and bringing enormous costs to health care. In efforts to reduce the burden of the disease, computational models have been developed to predict cartilage degeneration onset and progression. Current knee joint models have shed light on