2018 Nobel Prize in Physiology or Medicine
jointly to James P. Allison and Tasuku Honjo for their discovery of cancer therapy by inhibition of negative immune regulationSUMMARY Cancer kills millions of people every year and is one of humanity’s greatest health challenges. By stimulating the inherent ability of our immune system to attack tumor cells this year’s Nobel Laureates have established an entirely new principle for cancer therapy. James P. Allison studied a known protein that functions as a brake on the immune system. He realized the potential of releasing the brake and thereby