Skin cells from frontotemporal dementia patients may prove useful in revealing disease mechanisms and in biomarker and drug research
A new study from the University of Eastern Finland suggests that skin fibroblasts from frontotemporal dementia patients may be useful in investigating underlying disease mechanisms as well as in biomarker and drug research.Frontotemporal dementia (FTD) is the second most common cause of dementia in the working age population. The most common genetic cause of FTD is the C9orf72 hexanucleotide repeat expansion. This expansion is exceptionally common in Finnish FTD patients. Currently, there are no efficient therapies for FTD, it is challenging to diagnose, and the disease mechanisms remain