Karolinska University Hospital First to Give Stem Cells to Foetus with Severe Osteoporosis
A new treatment is being trialled to help children born with a severe variant of osteoporosis, osteogenesis imperfecta. It is the first clinical trial in the world in which bone-forming stem cells are given before birth. The hope is that this will increase the child's chances of building a functioning skeleton.Osteogenesis imperfecta is a congenital genetic disorder in which the collagen type 1 protein is defective, or not produced in sufficient amounts, preventing the bones from storing enough calcium, and growing strong. The skeleton is also remodelled too quickly, which contributes to