Many unexpected genetic variants hamper personalised medicine
In recent decades much hope was based on the development of personalised drug treatments, in which genetic tests determine the choice and optimal dose of medication for each individual patient. However, the real breakthrough is still to be seen, and now researchers at Karolinska Institutet show in two separate scientific papers that many more gene variants affect how a person responds to medication than previously thought – and thus that today’s analytical tools are too coarse.“For the individual patient, the tests used today don’t give enough information, which means that if we’re to