Mutation-carriers with metastatic melanoma responded surprisingly well to immunotherapy
We now know that there are three different routes into the central auditory system, instead of just one
We hope to develop a clinically expedient way of identifying individuals at risk of developing overweight and type 2 diabetes
Our study shows that if we imagine the movement but we do not physically perform it, real touch will still feel less intense
We’ve discovered that the muscles regulate oxygen consumption in a very precise way using the oxygen-sensitive enzyme FIH
The prescription of lithium has decreased steadily in recent years, but our results show that lithium should remain the first line of treatment for patients with bipolar disorder
Our results may be beneficial for the development of exercise programmes, particularly those designed for an ageing population
We already have results indicating that many more cell types than previously thought are involved in neurovascular diseases such as Alzheimer’s and brain tumours
The results show that it’s important to evaluate neonate vitality at both five and ten minutes, even if the score is normal at five
This is a unique study, since we’ve been able to analyse a large number of people with objective measures of physical activity for up to 15 years
Our results reveal a lack of equal treatment whereby psychiatric patients don’t seem to receive the care they need
Since allergies often debut during childhood it is of particular interest to study if children’s environment and lifestyle affect the development of these diseases
Modern humans are without doubt predators, but we probably evolved from a prey species, and some aspects of this characteristic remain
Our study shows that the astrocytes play an important part in the regulation of breathing by affecting the neurons and their network activity
This type of operation with a relatively low risk of complications is possibly an under-used therapeutic alternative
Previously, research has focused heavily on individual components, but the immune system is incredibly complex, involving many specialised cell types, and we think the important thing is precisely the interaction between these cells
Our results are of interest to other countries such as the USA, which is about to change its methods
After terror attacks, sensitive people might be afraid even if they themselves were not present
The manufacturing process is based on the method spiders use to keep their extremely easily aggregated proteins soluble for silk-spinning
This study increases our understanding of how genes are regulated in cells and further aids us in deciphering the grammar written into DNA
We need to ask about aggressive behaviour towards others when we assess and treat self-harming individuals, but we also need to ask about self-harm when we assess and treat aggressive individuals
We now have a simple tool for identifying and sorting the cells, which benefits future stem cell research and basic research on early embryonic development
Although this might seem simple and obvious, the impact of the hydraulic force on the heart’s filling pattern has been overlooked
The diabetes trend is largely driven by lifestyle factors, so to reduce your risk of diabetes you should not use tobacco, avoid being overweight and be physically active.
If we can introduce a more accurate way of testing for prostate cancer, we’ll spare patients unnecessary suffering and save resources for society.
The possibility of preventing or slowing down the spread of cancer cells via the lymphatic system is an attractive one, as it could reduce the risk of metastasis to other organs.
The study will form the basis of new guidelines from the WHO, which will recommend that midwives be allowed to handle the treatment of incomplete abortions.
Since bariatric surgery followed by pregnancy has both positive and negative effects, these women, when expecting, should be regarded as risk pregnancies.
We have created a much more detailed map of the cells of the brain that describes each cell type in detail and shows which genes are active in it.
What’s particularly exciting is that we’ve managed to translate laboratory findings into clinical application.
It's possible that this work opens up a new pharmacological principle in the treatment of depression.
Our current view of both the occurrence and treatment of obesity is far too narrow, since we talk almost exclusively about diet and exercise.
De Lange is a frontrunner in the field of telomeres, so we are very pleased to have her give this year's Nicholson Lecture
We believe that these very promising findings represent major advances towards the clinical translation of tissue engineered esophagi.
That existing anticancer agents hit the MTH1 shows that the concept really works. Now that we understand the mechanism, we can develop very selective inhibitors.
This is an entirely new mechanism for cancer treatment. A possible medicine based on this principle would therefore attack the glioblastoma in an entirely new way.
As many as nearly 30 per cent of the adolescents clustered in the 'invisible' group that had a high level of psychopathological symptoms.
It has not previously been observed that the inhibition of MYC affects tumour cells in this way
Oligonucleotide-based drugs are already available, and it’s very possible that our method could be used to produce purer and cheaper versions of these drugs.