Mechanism that converts white fat to brown identified
[PRESS RELEASE 5 January 2018] An international team of researchers led from Karolinska Institutet have, in experiments on mice, pinpointed a mechanism for the conversion of energy-storing white fat into energy-expending brown fat. The study is published in the Journal of Experimental Medicine.Obesity is a major global health issue, affecting all age groups. Obesity increases the risk of several serious human diseases, including cardiovascular disease, type 2 diabetes and cancer. Despite this knowledge, effective drugs for the treatment of obesity and related metabolic disease are lacking.