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Sahlgrenska Academy is the medical faculty at the University of Gothenburg. Education and research are conducted within the fields of pharmacy, medicine, odontology and health care sciences. https://www.gu.se/en/sahlgrenska-akademin

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    The study clearly shows that it is possible to achieve an immunological antibody memory with mucosal vaccination and that the memory cells that are created in connection with this type of vaccination are unique and cannot be achieved through traditional vaccination methods.
    Professor Nils Lycke
    The study shows that children who have had their thymus gland removed as infants have a greatly altered immune system at 18 years of age. This can be compared to how it normally appears at 65-70 years of age.
    Judith Gudmundsdottir, Sahlgrenska academy, University of Gothenburg
    We find that low but commonly used doses of SSRIs are more effective than placebo but clearly less effective than higher doses.
    Fredrik, Hieronymus, PhD student at Sahlgrenska Academy, University of Gothenburg
    There were more pronounced differences between male and female perpetrators with adult victims compared with when the victim was a child (under 15 years).
    Thomas Nilsson, Researcher at Sahlgrenska Academy, Sweden
    This information can help to establish midwifery as a profession in South Asia.
    Malin Bogren, researcher at the Sahlgrenska Academy
    More lives could potentially be saved if fewer babies slept on their stomachs or were placed on their sides, if fewer mothers smoked during pregnancy and if infants slept in their own beds in their parents’ bedroom during the first three months.
    Per Möllborg, The Sahlgrenska Academy
    This is good news for anyone with type 1 diabetes.
    Isabelle Steineck, researcher at the Sahlgrenska Academy
    Socioeconomic factors may pose a greater danger than traditional risk factors.
    Araz Rawshani, researcher at the Sahlgrenska Academy
    As long as there is a shortage of organs available, one cannot really be judgmental.
    Annette Lennerling, researcher at the Sahlgrenska Academy
    The results underline the importance of reducing our exposure to cadmium.
    Björn Fagerberg, researcher at the Sahlgrenska Academy
    It would be worthwhile offering silent spaces between deliverie.
    Sofie Fredriksson, researcher at the Sahlgrenska Academy
    The support for these drugs exerting an antidepressant impact is very robust.
    Elias Eriksson, professor at the Sahlgrenska Academy
    We have identified the factors that influence survival after the age of 50.
    Lars Wilhelmsen, researcher at the Sahlgrenska Academy
    Even people in their late 90s have sexual feelings.
    Nils Beckman, researcher at the Sahlgrenska Academy
    There has not been any consensus about the recommended surgical procedure.
    Torsten Olbers, researcher at the Sahlgrenska Academy
    About half of the IBS patients improved significantly.
    Lena Böhn, researcher at the Sahlgrenska Academy
    Our study shows that ghrelin plays a role in natural reward mechanisms like sex.
    Elisabet Jerlhag Holm, researcher at the Sahlgrenska Academy
    In the next five years, the technique could be introduced as a new treatment.
    Filip Bergquist, researcher at the Sahlgrenska Academy
    Our results underscore the importance of intensive, long-term prevention.
    Petra Redfors, researcher at the Sahlgrenska Academy
    The vaccine that we are developing will be of global benefit.
    Astrid von Mentzer, researcher at the Sahlgrenska Academy
    Our dream is to be able to grow complete organs.
    Suchitra Sumitran-Holgersson, researche at the Sahlgrenska Academy
    Half of the families experienced a large or very large improvement
    Mats Johnson, researcher at the Sahlgrenska Academy
    The method works, and we can use it to increase the number of donated lungs.
    Andreas Wallinder, researcher at the Sahlgrenska Academy
    Patients accept the treatment very well.
    Telmo Ramos, researcher at the Sahlgrenska Academy
    It gives us scientific evidence that the concept of uterus transplantation can be used
    Mats Brännström, Professor at the University of Gothenburg
    Steps must be taken to improve treatment.
    Charlotta Ljungman, researcher at the Sahlgrenska Academy
    Studying how diseases change throughout history can teach us more about how current diseases arise.
    Jakub Kwieciński, researcher at the Sahlgrenska Academy
    We need to identify the specific factors on dairy farms that strengthens the protection.
    Anna_Carin Lundell, researcher at the Sahlgrenska Academy
    There may be a built-in biological clock that is affected by the moon.
    Michael Smith, researcher at the Sahlgrenska Academy
    We have shown that Internet treatment actually works out in the field.
    Marie Kivi, researcher at the University of Gothenburg
    Children are very vulnerable in traffic.
    Eva Olofsson, researcher at the Sahlgrenska Academy
    A concussion, such as from a knockout, can take more than four months to heal.
    Sanna Neselius, researcher at the Sahlgrenska Academy
    We know very little about how the infection affects otherwise healthy people.
    Christine Wennerås, researcher at the Sahlgrenska Academy
    The tract area is important for the uptake of nutrients and drugs.
    Lars Fändriks, researcher at the Sahlgrenska Academy
    The risk for kidney damage caused by cadmium is lower than previously believed.
    Magnus Åkerström, researcher at the Sahlgrenska Academy
    Drug-related morbidity is a significant public health problem
    Katja Hakkarainen, researcher at the Sahlgrenska Academy
    Within five years the mass spectrometers will have moved into the hospitals.
    Gunnar C Hansson, researcher at the Sahlgrenska Academy
    We hope this can be a new clinical tool in sports medicine.
    Henrik Zetterberg, researcher at the Sahlgrenska Academy
    Many parents simply do not see the increase in growth.
    Susanne Regberg, researcher at the Sahlgrenska Academy
    We can link healthy eating habits to reduced risk of preterm delivery.
    Linda Englund-Ögge, researcher at the Sahlgrenska Academy
    In a scientific and medical perspective, the transplants have been successful.
    Mats Brännström, researcher at the University of Gothenburg
    Our nerve fibers are finely tuned to respond to another person's caressing stroke.
    Rochelle Ackerley, researcher at the Sahlgrenska Academy
    Facebook offers a unique opportunity for psychological research.
    Danilo Garcia, researcher at the Sahlgrenska Academy
    It is about finding research areas witth the potential to drastically reduce health care costs
    Inger Ekman, researcher at the Sahlgrenska Academy
    This is an entirely new pharmacological perspective
    Elisabet Jerlhag, researcher at the Sahlgrenska Academy
    With 260 million football players in the world, preventive measures could help many.
    Jaakko Ryynänen, researcher at the Sahlgrenska Academy
    We were surprised by these results.
    Gunilla Krantz, researcher at the Sahlgrenska Academy
    There is some controversy in that we have not found any viruses.
    Erik Larsson, researcher at the Sahlgrenska Academy
    This is of tremendous value to the patients.
    Eva Olausson, researcher at the Sahlgrenska Academy
    Just as the Beatles sang, most people understand that money can't buy you happiness or love.
    Danilo Garcia, researcher at the Sahlgrenska Academy
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    Omega-3 and Omega-6 Supplement Improves Reading for Children

    Supplement of omega-3 and omega-6 fatty acids may improve reading skills of mainstream schoolchildren, according to a new study from Sahlgrenska Academy, at the University of Gothenburg, Sweden. Children with attention problems, in particular, may be helped in their reading with the addition of these fatty acids.The study included 154 schoolchildren from western Sweden in grade 3, between nine and ten years old. The children took a computer-based test (known as the Logos test) that measured their reading skills in a variety of ways, including reading speed, ability to read nonsense words

    The mucosa forms special immunological memory—a breakthrough for vaccine research

    If a vaccine is to protect the intestines and other mucous membranes in the body, it also needs to be given through the mucosa, for example as a nasal spray or a liquid that is drunk. The mucosa forms a unique immunological antibody memory that does not occur if the vaccine is given by injection. This has been shown by a new study from Sahlgrenska Academy, Sweden,  published in the prestigious Nature Communications.Immunological memory is the secret to human protection against various diseases and the success of vaccines. It allows our immune system to quickly recognize and neutralize

    The colon is defended from bacteria by a self-sacrificing sentinel cell

    A lone Sentinel cell monitors and coordinates the defense of the entrance to the colon’s most sensitive parts. The Sentinel cell detects nearby bacteria and signals to a line of defensive cells to send out a cascade of mucus to push away the invaders. As a final self-sacrificing action the cell commits suicide and ejects itself into the intestinal lumen.Researchers at the Sahlgrenska Academy, University of Gothenburg, have discovered a new group of cells that can wash away the bacteria that have penetrated through the protective mucus barrier. The discovery, published in the journal Science,

    Many infants that undergo cardiac surgery develop an aged immune system

    Infants that undergo cardiac surgery often have their thymus gland removed. The thymus performs important functions during the development of the immune system and a new study at Sahlgrenska Academy shows that infants, whose thymus was surgically removed, have an immune system at 18 years of age comparable to one normally seen in 65-70 year-olds.Approximately 1 percent of all children are born with heart defects and, since the 1980s, the number of children undergoing corrective heart surgery during the newborn period has increased.  During major cardiac surgery where the heart is

    Higher doses of antidepressants are associated with better treatment response

    In contrast to what has previously been claimed, low doses of antidepressants are clearly less effective than higher ones. This is the principal finding of a new study from the Sahlgrenska Academy at the University of Gothenburg in Sweden. The authors also suggest that antidepressants, when used at an optimal dose, are considerably more effective than usually assumed.Selective serotonin reuptake inhibitors, or SSRIs, are antidepressants influencing the activity of the neurotransmitter serotonin. While the SSRIs remain the most commonly prescribed type of antidepressant, it has recently been

    Major differences between women and men who commit deadly violence

    Women who commit deadly violence are different in many ways from male perpetrators, both in terms of the most common victims, the way in which the murder is committed, the place where it is carried out and the perpetrator’s background. This is shown by a new study that also investigated homicide trends over time in Sweden.Sweden is in the group of countries with the lowest number of murders per capita. As in other parts of the world, the majority of cases of deadly violence are committed by men: In nine cases out of ten, the perpetrator is a man.   It is also men that have been the main

    Sex hormones appear to be involved in the development of autism

    Human social capabilities might be associated with genetic variations in sex hormone related genes. Such were the results of a new doctoral study at Sahlgrenska Academy that studied sex hormone involvement in social behavior and the development of autism.Currently, there is no pharmacological treatment for autism spectrum syndrome, thus understanding its origin is important for the discovery of future treatments.  Social behavior is regulated by the brain, which is affected by sex hormones, in both humans and other animals. A contributing factor of autism is believed to be higher levels

    Environmental pollution with antibiotics leads to resistance

    More and more people are infected with antibiotic resistant bacteria. But how do bacteria become resistant? A recent doctoral thesis from the Centre for Antibiotic Resistance Research at University of Gothenburg has investigated the role of the environment in the development of antibiotic resistance.“An important question we asked was how low concentrations of antibiotics that can favour the growth of resistant bacteria in the environment”, says Johan Bengtsson-Palme, author of the thesis. “Based on our analyses, we propose emission limits for 111 antibiotics that should not be exceeded

    New study and database on biomarkers - a major aid in Alzheimer’s research

    In a new study published in Lancet Neurology, researchers at Sahlgrenska Academy have been able to show which blood and cerebrospinal fluid biomarkers that best differentiate between patients with Alzheimer’s disease and controls. Parallel to the study, the researchers developed a large database that gathers data on biomarkers in Alzheimer’s and other forms of dementia.Alzheimer’s disease is the most common form of dementia. It causes enormous suffering in both the patients and relatives, and the disease costs society more than all cardiovascular and cancer healthcare combined. An

    Free pap screening did not increase participation

    1,562 women were offered free gynecological pap test screening in three socioeconomically disadvantaged areas in Gothenburg, in 2013. A new study from Sahlgrenska Academy, Närhälsan and the Regional Cancer Center West now shows that these women did not participate to a greater degree than the group that was offered the screening for the usual fee.Not participating in gynecological pap test screening is the single greatest risk factor in Sweden for acquiring and dying of cervical cancer. 1,562 women in the Gothenburg areas of Angered, Bergsjön and Biskopsgården were offered free pap test

    Strategy for increasing survival of mothers and newborns in South Asia

    In several South Asian countries, midwifery is not an established profession. As a result, complications in both mothers and newborns are extremely common. Sweden researchers is presenting a new strategy on how the midwifery profession can be established in low-income countries is presented, which could also improve the health of mothers and newborns.The goal of increased maternal survival is one of the UN’s Millennium Development Goals with the lowest degree of fulfillment. An important strategy for improving maternal and child health is well-educated midwives. However, in many of the

    Infants should sleep in their own beds to reduce the risk of sudden infant death syndrome

    The advice given to reduce the risk of sudden infant death syndrome, SIDS, has worked well, but the potential to save more lives exists. In addition to sleeping on their backs, infants should sleep in their own beds for the first few months to reduce the risk of sudden infant death. A new doctoral thesis at Sahlgrenska Academy at University of Gothenburg has explored these issues.In the early 1990s, the Swedish National Board of Health and Welfare went out with advice to new parents to reduce the number of children who die each year from SIDS. The advice stated that children sleep safest on

    Researchers’ advice to save the relationships of parents of small children

    According to Statistics Sweden, 30 percent of all parents of young children in Sweden separate. Researchers at the University of Gothenburg have mapped the most important factors behind the separations and divorces - and offer five tips that can save the relationship.According to 2012 statistics from Statistics Sweden, one out of three Swedish couples that have small children get separated. The average age of the first child at the time of the separation or divorce is 4 years and 8 months.   In a study at the Sahlgrenska Academy of the University of Gothenburg, 452 parents answered a

    NFL plasma concentration a sensitive new biomarker for identifying central nervous system injury

    Researchers at Sahlgrenska Academy, University of Gothenburg, have devised a method for detecting injury to the central nervous system by examining blood plasma. The approach, which has been tested thus far on individuals with HIV-associated brain injury, opens the door to diagnosis of a wide range of neurodegenerative disorders without taking invasive samples of the cerebrospinal fluid.While the level of the neurofilament light protein (NFL) in the cerebrospinal fluid represents a sensitive marker of neuronal injury, its clinical potential is limited by the need to perform lumbar puncture.

    The gut microbiota can influence the effectiveness of dietary treatments

    Why a dietary treatment works for some but not others seems to depend on interactions between the gut microbiota and the diet. A new study, published in Cell Metabolism, shows that people with better control of blood sugar after eating barley kernel bread also have a different balance of microbes in the gut.Dietary interventions can be used to improve the metabolism of humans, and they also have a major impact on the gut microbiota. Previous studies at the Sahlgrenska Academy have shown that the gut microbiota is altered in metabolic diseases such as type 2 diabetes, and that the gut

    New treatment combination effective in individuals with complex type 2 diabetes

    A new combination of drugs can help individuals with complex type 2 diabetes lower their blood sugar levels, reducing their weight and use fewer insulin doses. This is shown in a study published in The British Medical Journal.Individuals with type 2 diabetes who are treated with basal and mealtime insulin injections have few treatment options if their blood glucose is increased, other than increasing insulin doses. This often leads to a downward spiral with increased weight, which can have a negative effect on blood glucose. In this study Swedish researchers have evaluated the effect of

    Antioxidants cause malignant melanoma to metastasize faster

    Fresh research at Sahlgrenska Academy has found that antioxidants can double the rate of melanoma metastasis in mice. The results reinforce previous findings that antioxidants hasten the progression of lung cancer. According to Professor Martin Bergö, people with cancer or an elevated risk of developing the disease should avoid nutritional supplements that contain antioxidants.Researchers at Sahlgrenska Academy, University of Gothenburg, demonstrated in January 2014 that antioxidants hastened and aggravated the progression of lung cancer. Mice that were given antioxidants developed

    Early testing can predict the stroke patients who will develop upper limb spasticity

    Many stroke patients suffer from spasticity of the arm that cause pain and impaired sensorimotor function. But there are ways of identifying such patients ahead of time so that they can obtain the earliest possible treatment. Researchers at Sahlgrenska Academy have completed a study of stroke patients in the Gothenburg area.Spasticity and related complications are relatively common after stroke, leading to poorer joint range of motion, greater pain and less sensitivity in the arm one year later. A study at Sahlgrenska Academy, University of Gothenburg, has found that the Fugl-Meyer

    Diabetes medication could be used to treat alcohol dependence

    A new study on mice and rats at Sahlgrenska Academy shows that a medication used for diabetes and obesity also could be a valuable tool for the treatment of alcohol dependence.Alcohol dependence causes morbidity as well as mortality and is major health problem in today’s society. The costs for alcohol dependence in Sweden are estimated to be around SEK 45 billion per year. Nearly 5 percent of the adult population in Sweden have been diagnosed with alcohol dependence, which corresponds to approximately 300 000 people. Even more Swedes have harmful alcohol consumption. Indeed, approximately

    Female gamers a new risk group for overweight

    Young women who play computer games are a new risk group for developing overweight and obesity. This is the finding of a study that includes more than 2,500 Swedes in their twenties.In the current study, around 2,500 young adults between the ages of 20 and 24 responded to a survey on three different occasions: in 2007, 2008 and 2012. Researchers at Sahlgrenska Academy used the survey to investigate whether the amount of time young people spend e-mailing, chatting or playing computer games in their free time affects their BMI. The results show that women of normal weight who played

    Insulin pump reduces mortality from cardiovascular disease by almost 50%

    People with type 1 diabetes who use insulin pump therapy face almost 50% less risk of dying from cardiovascular disease than those who take insulin by multiple daily injections. The British Medical Journal has published a study conducted at Sahlgrenska Academy.Based on the Swedish National Diabetes Register, researchers monitored 18,168 Swedes with type 1 diabetes from 2005 to 2012. While 2,441 of the subjects used insulin pump therapy, the others relied on multiple daily injections. The study found that insulin pump users had a substantially lower risk of dying of cardiovascular disease

    Mortality rates higher among people with diabetes whose socioeconomic status is low

    Low income and educational level almost triples the risk that people with type 1 diabetes will die of cerebral infarction. A doctoral thesis at Sahlgrenska Academy also showed the conclusion that type diabetes 1 is declining among young people to be unfounded.Approximately 400,000 Swedes have diabetes, and type 1 diabetes is the second most common chronic disease among children and young adults. Newer studies have suggested that 15-34 year-olds are developing type 1 diabetes at a slower rate than previously. A recent doctoral thesis at Sahlgrenska Academy, University of Gothenburg,

    Trend – searching for organ donors in social media

    It is becoming increasingly common for patients to search in social media to find live organ donors. In a scientific study, researchers in Europe have examined the phenomenon and have a number of recommendations.In the United States, transplants are routinely performed where the living donor is recruited through what is known as a “public solicitation,” which means that the receiving patient has actively “advertised” for an organ, for instance via social media. In Europe, this approach is seen less often. A donation after a public appeal or solicitation has also been criticized by the

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